E88.4

E88.4: Mitochondrial metabolism disorders

Non-billable headerICD-10-CM

E88.4 is a non-billable header ICD-10-CM code for mitochondrial metabolism disorders. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

disorders of pyruvate metabolism (E74.4)
Kearns-Sayre syndrome (H49.81)
Leber's disease (H47.22)
Leigh's encephalopathy (G31.82)
Mitochondrial myopathy, NEC (G71.3)
Reye's syndrome (G93.7)

Excludes1 inherited from the categories above E88.4

A category’s note binds every code beneath it.

Written on E88: Other and unspecified metabolic disorders

histiocytosis X (chronic) (C96.6)

Other codes that can never be billed with E88.4

Their own Excludes1 notes name this code, so the conflict is not listed above.

G71.3Mitochondrial myopathy, not elsewhere classified

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead E88.4

5 child codes. Green means billable.