MCMedicalCodingSoftware
C96.6

C96.6: Unifocal Langerhans-cell histiocytosis

Billable / specific codeICD-10-CM

C96.6 is a billable, specific ICD-10-CM code for unifocal langerhans-cell histiocytosis. It is valid for submission on a claim.

Check C96.6 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
  • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Eosinophilic granuloma
  • Histiocytosis X, unifocal
  • Histiocytosis X NOS
  • Langerhans-cell histiocytosis NOS

Excludes1 inherited from the categories above C96.6

A category’s note binds every code beneath it.

Written on C96: Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue

  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Other codes that can never be billed with C96.6

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • C96.0Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
  • C96.5Multifocal and unisystemic Langerhans-cell histiocytosis
  • D76Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
  • E88Other and unspecified metabolic disorders
  • C77Secondary and unspecified malignant neoplasm of lymph nodes

Risk adjustment

C96.6 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 21 Lymphoma and Other Cancers0.671 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

C96.6 is named in 16 Medicare coverage policies: 16 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A54768Billing and Coding: Cardiac Blood Pool Imaging (Multiple Gated Acquisition Scanning- MUGA, Ventriculography) When Performed in Conjunction with Cardiotoxic Chemotherapy
  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A57224Billing and Coding: Respiratory Care
  • A57630Billing and Coding: Percutaneous Vertebral Augmentation (PVA) for Vertebral Compression Fracture (VCF)

Alphabetic index entries that lead here

  • Granuloma›eosinophilic
  • Histiocytosis›Langerhans' cell NEC
  • Histiocytosis›X NEC
  • Granuloma›bone›eosinophilic
  • Granuloma›bone›lung
  • Granuloma›eosinophilic›bone
  • Granuloma›eosinophilic›lung
  • Granuloma›lung›eosinophilic
  • Histiocytosis›Langerhans' cell NEC›unifocal(X)
  • Histiocytosis›mononuclear phagocytes NEC›Langerhans' cells
  • Histiocytosis›X NEC›chronic
  • Histiocytosis›X NEC›unifocal

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under C96

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.