MCMedicalCodingSoftware
E88

E88: Other and unspecified metabolic disorders

Non-billable headerICD-10-CM

E88 is a non-billable header ICD-10-CM code for other and unspecified metabolic disorders. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • histiocytosis X (chronic) (C96.6)

Use additional code

Add a secondary code to capture the detail described below.

  • codes for associated conditions

Other codes that can never be billed with E88

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • G71.3Mitochondrial myopathy, not elsewhere classified
  • P59Neonatal jaundice from other and unspecified causes
  • R64Cachexia
  • R73.0Abnormal glucose
  • R77Other abnormalities of plasma proteins

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead E88

8 child codes. Green means billable.

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.