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ICD-10-CM tabular list

Chapter 4: Endocrine, nutritional and metabolic diseases

E00-E89

Chapter 4 of the ICD-10-CM tabular list covers endocrine, nutritional and metabolic diseases, codes E00-E89. It holds 1,267 codes across 10 blocks, of which 971 are billable and 296 are header codes that cannot go on a claim. 345 (27%) require a 7th character.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

Additional guidance from the ICD-10-CM tabular list.

  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Risk adjustment in Chapter 4

410 of this chapter’s codes map to a CMS-HCC, which means the diagnosis carries a risk-adjustment payment when it is documented and coded to the level the record supports.

  • HCC 37 Diabetes with Chronic Complications
  • HCC 298 Severe Diabetic Eye Disease, Retinal Vein Occlusion, and Vitreous Hemorrhage
  • HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders
  • HCC 36 Diabetes with Severe Acute Complications
  • HCC 38 Diabetes with No, Glycemic, or Unspecified Complications
  • HCC 49 Specified Lysosomal Storage Disorders

Blocks in this chapter

ICD-10-CMFY2026-Apr· effective April 1, 2026