E22.0 — Acromegaly and pituitary gigantism
E22.0 is a billable, specific ICD-10-CM code for acromegaly and pituitary gigantism. It is valid for submission on a claim.
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Overproduction of growth hormone
Other codes that can never be billed with E22.0
These codes carry an Excludes1 note pointing at E22.0. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E22.0 alone.
- M26.0Major anomalies of jaw size
Risk adjustment
E22.0 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 51 Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders0.510 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
E22.0 is named in 8 Medicare coverage policies — 8 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A56531Billing and Coding: Octreotide Acetate for Injectable Suspension (Sandostatin® LAR Depot)
- A56551Billing and Coding: Visual Fields Testing
- A56612Billing and Coding: CT of the Head
- A56631Billing and Coding: Thoracic Aortography and Carotid, Vertebral, and Subclavian Angiography
How E22.0 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E22.0.
- Acromegaly, acromegalia
- Erdheim's syndrome(acromegalic macrospondylitis)
- Gigantism(cerebral) (hypophyseal) (pituitary)
- Launois' syndrome(pituitary gigantism)
- Macrospondylitis , acromegalic
- Scaglietti-Dagnini syndrome
- Hypophyseal, hypophysis›gigantism
- Marie's›disease or syndrome(acromegaly)
- Overproduction›growth hormone
- Syndrome›costovertebral
- Syndrome›Erdheim's
- Syndrome›Launois'
Related codes at this level
Codes that share E22. If E22.0 is not quite right, the correct code is usually one of these.
Questions about E22.0
- Is E22.0 a billable ICD-10-CM code?
- Yes. E22.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E22.0 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Disorders of other endocrine glands (E20-E35).
- What cannot be coded together with E22.0?
- E22.0 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.