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E27.0

E27.0Other adrenocortical overactivity

Billable / specific codeICD-10-CM

E27.0 is a billable, specific ICD-10-CM code for other adrenocortical overactivity. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • Cushing's syndrome (E24.-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Overproduction of ACTH, not associated with Cushing's disease
  • Premature adrenarche

Other codes that can never be billed with E27.0

These codes carry an Excludes1 note pointing at E27.0. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E27.0 alone.

  • E22Hyperfunction of pituitary gland

Risk adjustment

E27.0 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

E27.0 is named in 4 Medicare coverage policies 4 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A57204Billing and Coding: MRI and CT Scans of the Head and Neck
  • A57326Billing and Coding: Electrocardiograms
  • A57361Billing and Coding: Monitored Anesthesia Care
  • A57612Billing and Coding: Measurement of Salivary Hormones

How E27.0 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E27.0.

  • Adrenarche, premature
  • Schroeder's syndrome(endocrine hypertensive)
  • Slocumb's syndrome
  • Dysadrenocortismhyperfunction
  • Hyperadrenocorticismnot associated with Cushing's syndrome
  • Hyperfunctionadrenal cortex, not associated with Cushing's syndrome
  • HypersecretionACTH(not associated with Cushing's syndrome)
  • Overactiveadrenal cortex NEC
  • OverproductionACTH
  • Prematureadrenarche
  • Syndromeendocrine-hypertensive
  • SyndromeSchroeder's

Related codes at this level

Codes that share E27. If E27.0 is not quite right, the correct code is usually one of these.

Questions about E27.0

Is E27.0 a billable ICD-10-CM code?
Yes. E27.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E27.0 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Disorders of other endocrine glands (E20-E35).
What cannot be coded together with E27.0?
E27.0 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.