MCMedicalCodingSoftware
E27.1

E27.1: Primary adrenocortical insufficiency

Billable / specific codeICD-10-CM

E27.1 is a billable, specific ICD-10-CM code for primary adrenocortical insufficiency. It is valid for submission on a claim.

Check E27.1 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • Addison only phenotype adrenoleukodystrophy (E71.528)
  • amyloidosis (E85.-)
  • tuberculous Addison's disease (A18.7)
  • Waterhouse-Friderichsen syndrome (A39.1)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Addison's disease
  • Autoimmune adrenalitis

Risk adjustment

E27.1 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 51 Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders0.510 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

E27.1 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A57326Billing and Coding: Electrocardiograms
  • A57361Billing and Coding: Monitored Anesthesia Care
  • A59186Billing and Coding: Magnesium

Alphabetic index entries that lead here

  • Addison's›disease or syndrome(bronze)
  • Adrenalitis, adrenitis›autoimmune
  • Disease, diseased›bronze Addison's
  • Hypoadrenalism, hypoadrenia›primary
  • Hypoadrenocorticism›primary
  • Melanosis›addisonian
  • Melanosis›adrenal
  • Melanosis›suprarenal
  • Melasma›adrenal(gland)
  • Melasma›suprarenal(gland)
  • Atrophy, atrophic›adrenal›primary(autoimmune)
  • Atrophy, atrophic›suprarenal›primary

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E27

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.