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E27.5

E27.5: Adrenomedullary hyperfunction

Billable / specific codeICD-10-CM

E27.5 is a billable, specific ICD-10-CM code for adrenomedullary hyperfunction. It is valid for submission on a claim.

Check E27.5 with the rest of the claim: free scrubber

Code also

Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.

  • , if applicable:
  • malignant pheochromocytoma (C74.1-)
  • pheochromocytoma (benign) (D35.0-)
  • secondary hypertension (I15.2)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Adrenomedullary hyperplasia
  • Catecholamine hypersecretion

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E27.5 is named in 2 Medicare coverage policies: 2 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A57326Billing and Coding: Electrocardiograms
  • A57361Billing and Coding: Monitored Anesthesia Care

Alphabetic index entries that lead here

  • Hyperadrenalism
  • Hyperplasia, hyperplastic›adrenomedullary
  • Hypersecretion›adrenaline
  • Hypersecretion›adrenomedullary
  • Hypersecretion›catecholamine
  • Hypersecretion›epinephrine
  • Hypersecretion›medulloadrenal
  • Overproduction›catecholamine
  • Secretion›catecholamine, by pheochromocytoma
  • Hyperfunction›adrenal cortex, not associated with Cushing's syndrome›medulla
  • Hyperfunction›adrenal cortex, not associated with Cushing's syndrome›medulla›adrenomedullary
  • Increase, increased›function›adrenal›medulla

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E27

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.