MCMedicalCodingSoftware
E22.9

E22.9: Hyperfunction of pituitary gland, unspecified

Billable / specific codeICD-10-CM

E22.9 is a billable, specific ICD-10-CM code for hyperfunction of pituitary gland, unspecified. It is valid for submission on a claim.

Check E22.9 with the rest of the claim: free scrubber

Excludes1 inherited from the categories above E22.9

A category’s note binds every code beneath it.

Written on E22: Hyperfunction of pituitary gland

  • Cushing's syndrome (E24.-)
  • Nelson's syndrome (E24.1)
  • overproduction of ACTH not associated with Cushing's disease (E27.0)
  • overproduction of pituitary ACTH (E24.0)
  • overproduction of thyroid-stimulating hormone (E05.8-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E22.9 is named in 5 Medicare coverage policies: 5 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56551Billing and Coding: Visual Fields Testing
  • A56612Billing and Coding: CT of the Head
  • A56631Billing and Coding: Thoracic Aortography and Carotid, Vertebral, and Subclavian Angiography
  • A57204Billing and Coding: MRI and CT Scans of the Head and Neck

Alphabetic index entries that lead here

  • Hyperpituitarism
  • Hyperfunction›pituitary(gland) (anterior)
  • Hypersecretion›hormone›pituitary
  • Increase, increased›function›pituitary(gland) (anterior) (lobe)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E22

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.