MCMCB Pro
D81.810

D81.810Biotinidase deficiency

Billable / specific codeICD-10-CM

D81.810 is a billable, specific ICD-10-CM code for biotinidase deficiency. It is valid for submission on a claim.

Risk adjustment

D81.810 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D81.810 is named in 16 Medicare coverage policies 16 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56638Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
  • A56642Billing and Coding: Gastrointestinal Pathogen (GIP) Panels Utilizing Multiplex Nucleic Acid Amplification Techniques (NAATs)
  • A57205Billing and Coding: Oximetry Services
  • A57224Billing and Coding: Respiratory Care

How D81.810 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D81.810.

  • Deficiency, deficientbiotinidase
  • Immunodeficiencycombinedbiotin-dependent carboxylasebiotinidase

Related codes at this level

Codes that share D81.81. If D81.810 is not quite right, the correct code is usually one of these.

Questions about D81.810

Is D81.810 a billable ICD-10-CM code?
Yes. D81.810 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D81.810 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Certain disorders involving the immune mechanism (D80-D89).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.