D80.0: Hereditary hypogammaglobulinemia
D80.0 is a billable, specific ICD-10-CM code for hereditary hypogammaglobulinemia. It is valid for submission on a claim.
Check D80.0 with the rest of the claim: free scrubberInclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Autosomal recessive agammaglobulinemia (Swiss type)
- X-linked agammaglobulinemia [Bruton] (with growth hormone deficiency)
Other codes that can never be billed with D80.0
Their own Excludes1 notes name this code, so the conflict is not listed above.
- D81Combined immunodeficiencies
Risk adjustment
D80.0 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.
Medicare coverage
D80.0 is named in 27 Medicare coverage policies: 27 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.
- A52507External Infusion Pumps - Policy Article
- A52509Intravenous Immune Globulin - Policy Article
- A54660Billing and Coding: Coverage of Intravenous Immune Globulin for Treatment of Primary Immune Deficiency Diseases in the Home – Medicare Benefit Policy Manual, Chapter 15, 50.6
- A55717Billing and Coding: Lab: Flow Cytometry
Alphabetic index entries that lead here
- Bruton's X-linked agammaglobulinemia
- Agammaglobulinemia›autosomal recessive(Swiss type)
- Agammaglobulinemia›Bruton's X-linked
- Agammaglobulinemia›congenital sex-linked
- Agammaglobulinemia›hereditary
- Agammaglobulinemia›Swiss type(autosomal recessive)
- Agammaglobulinemia›X-linked(with growth hormone deficiency) (Bruton)
- Hypogammaglobulinemia›hereditary
- Immunodeficiency›autosomal recessive, Swiss type
- Absence›gamma globulin in blood›hereditary
- Deficiency, deficient›gammaglobulin in blood›hereditary
- Syndrome›antibody deficiency›congenital
Code history
Unchanged in every release from FY2024 to FY2027.
Other codes under D80
- D80.1Nonfamilial hypogammaglobulinemia
- D80.2Selective deficiency of immunoglobulin A [IgA]
- D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
- D80.4Selective deficiency of immunoglobulin M [IgM]
- D80.5Immunodeficiency with increased immunoglobulin M [IgM]
- D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
- D80.7Transient hypogammaglobulinemia of infancy
- D80.8Other immunodeficiencies with predominantly antibody defects
- D80.9Immunodeficiency with predominantly antibody defects, unspecified