D80.4 — Selective deficiency of immunoglobulin M [IgM]
D80.4 is a billable, specific ICD-10-CM code for selective deficiency of immunoglobulin m [igm]. It is valid for submission on a claim.
Risk adjustment
D80.4 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
D80.4 is named in 35 Medicare coverage policies — 35 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52507External Infusion Pumps - Policy Article
- A52509Intravenous Immune Globulin - Policy Article
- A54660Billing and Coding: Coverage of Intravenous Immune Globulin for Treatment of Primary Immune Deficiency Diseases in the Home – Medicare Benefit Policy Manual, Chapter 15, 50.6
- A55717Billing and Coding: Lab: Flow Cytometry
How D80.4 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D80.4.
- Absence›immunoglobulin, isolated NEC›IgM
- Deficiency, deficient›immunity›IgM
- Deficiency, deficient›immunoglobulin, selective›M(IgM)
- Immunodeficiency›selective, immunoglobulin›M(IgM)
Related codes at this level
Codes that share D80. If D80.4 is not quite right, the correct code is usually one of these.
- D80.0Hereditary hypogammaglobulinemia
- D80.1Nonfamilial hypogammaglobulinemia
- D80.2Selective deficiency of immunoglobulin A [IgA]
- D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
- D80.5Immunodeficiency with increased immunoglobulin M [IgM]
- D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
- D80.7Transient hypogammaglobulinemia of infancy
- D80.8Other immunodeficiencies with predominantly antibody defects
- D80.9Immunodeficiency with predominantly antibody defects, unspecified
Questions about D80.4
- Is D80.4 a billable ICD-10-CM code?
- Yes. D80.4 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does D80.4 sit in the tabular list?
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Certain disorders involving the immune mechanism (D80-D89).