MCMedicalCodingSoftware
D80.5

D80.5: Immunodeficiency with increased immunoglobulin M [IgM]

Billable / specific codeICD-10-CM

D80.5 is a billable, specific ICD-10-CM code for immunodeficiency with increased immunoglobulin m [igm]. It is valid for submission on a claim.

Check D80.5 with the rest of the claim: free scrubber

Risk adjustment

D80.5 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 115 Specified Immunodeficiencies and White Blood Cell Disorders0.565 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D80.5 is named in 27 Medicare coverage policies: 27 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52507External Infusion Pumps - Policy Article
  • A52509Intravenous Immune Globulin - Policy Article
  • A54660Billing and Coding: Coverage of Intravenous Immune Globulin for Treatment of Primary Immune Deficiency Diseases in the Home – Medicare Benefit Policy Manual, Chapter 15, 50.6
  • A55717Billing and Coding: Lab: Flow Cytometry

Alphabetic index entries that lead here

  • Immunodeficiency›X-linked, with increased IgM
  • Immunodeficiency›with›increased immunoglobulin M(IgM)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D80

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.