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D80.9

D80.9Immunodeficiency with predominantly antibody defects, unspecified

Billable / specific codeICD-10-CM

D80.9 is a billable, specific ICD-10-CM code for immunodeficiency with predominantly antibody defects, unspecified. It is valid for submission on a claim.

Risk adjustment

D80.9 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

D80.9 is named in 13 Medicare coverage policies 13 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)
  • A56841Billing and Coding: Vitamin D; 25 hydroxy, includes fraction(s), if performed
  • A57718Billing and Coding: Vitamin D Assay Testing
  • A57736Billing and Coding: Vitamin D Assay Testing

How D80.9 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D80.9.

  • Defect, defectiveantibody immunodeficiency
  • Syndromeantibody deficiency
  • Deficiency, deficientimmunityhumoral
  • Immunodeficiencywithantibody defects

Related codes at this level

Codes that share D80. If D80.9 is not quite right, the correct code is usually one of these.

Questions about D80.9

Is D80.9 a billable ICD-10-CM code?
Yes. D80.9 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D80.9 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Certain disorders involving the immune mechanism (D80-D89).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.