MCMedicalCodingSoftware
D81.8

D81.8: Other combined immunodeficiencies

Non-billable headerICD-10-CM

D81.8 is a non-billable header ICD-10-CM code for other combined immunodeficiencies. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 inherited from the categories above D81.8

A category’s note binds every code beneath it.

Written on D81: Combined immunodeficiencies

  • autosomal recessive agammaglobulinemia (Swiss type) (D80.0)

Other codes that can never be billed with D81.8

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E79Disorders of purine and pyrimidine metabolism

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead D81.8

3 child codes. Green means billable.

Other codes under D81

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.