D81.9: Combined immunodeficiency, unspecified
D81.9 is a billable, specific ICD-10-CM code for combined immunodeficiency, unspecified. It is valid for submission on a claim.
Check D81.9 with the rest of the claim: free scrubberInclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Severe combined immunodeficiency disorder [SCID] NOS
Other codes that can never be billed with D81.9
Their own Excludes1 notes name this code, so the conflict is not listed above.
- E79Disorders of purine and pyrimidine metabolism
Risk adjustment
D81.9 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 114 Common Variable and Combined Immunodeficiencies2.262 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.
Medicare coverage
D81.9 is named in 17 Medicare coverage policies: 17 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.
- A52507External Infusion Pumps - Policy Article
- A52509Intravenous Immune Globulin - Policy Article
- A54660Billing and Coding: Coverage of Intravenous Immune Globulin for Treatment of Primary Immune Deficiency Diseases in the Home – Medicare Benefit Policy Manual, Chapter 15, 50.6
- A55717Billing and Coding: Lab: Flow Cytometry
Alphabetic index entries that lead here
- Agammaglobulinemia›lymphopenic
- Immunodeficiency›combined
- Immunodeficiency›severe combined(SCID)
- Syndrome›combined immunity deficiency
- Syndrome›immunity deficiency, combined
- Agammaglobulinemia›with›lymphopenia
- Deficiency, deficient›immunity›combined
- Immunodeficiency›combined›severe(SCID)
- Syndrome›immunodeficiency›combined
Code history
Unchanged in every release from FY2024 to FY2027.
Other codes under D81
- D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.3Adenosine deaminase [ADA] deficiency
- D81.4Nezelof's syndrome
- D81.5Purine nucleoside phosphorylase [PNP] deficiency
- D81.6Major histocompatibility complex class I deficiency
- D81.7Major histocompatibility complex class II deficiency
- D81.8Other combined immunodeficiencies