D81.82: Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
D81.82 is a billable, specific ICD-10-CM code for activated phosphoinositide 3-kinase delta syndrome [apds]. It is valid for submission on a claim.
Check D81.82 with the rest of the claim: free scrubberCode also
Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease
Other codes that can never be billed with D81.82
Their own Excludes1 notes name this code, so the conflict is not listed above.
- E79Disorders of purine and pyrimidine metabolism
Risk adjustment
D81.82 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 114 Common Variable and Combined Immunodeficiencies2.262 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.
Medicare coverage
D81.82 is named in 16 Medicare coverage policies: 16 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.
- A52507External Infusion Pumps - Policy Article
- A52509Intravenous Immune Globulin - Policy Article
- A56464Billing and Coding: Flow Cytometry
- A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)
Alphabetic index entries that lead here
- Disease, diseased›p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI]
- Syndrome›activated phosphoinositide 3-kinase delta syndrome [APDS]
Code history
Unchanged in every release from FY2024 to FY2027.