D81.82 — Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
D81.82 is a billable, specific ICD-10-CM code for activated phosphoinositide 3-kinase delta syndrome [apds]. It is valid for submission on a claim.
Code also
Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease
Risk adjustment
D81.82 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 114 Common Variable and Combined Immunodeficiencies2.262 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
D81.82 is named in 25 Medicare coverage policies — 25 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A52507External Infusion Pumps - Policy Article
- A52509Intravenous Immune Globulin - Policy Article
- A56464Billing and Coding: Flow Cytometry
- A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)
How D81.82 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D81.82.
- Disease, diseased›p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI]
- Syndrome›activated phosphoinositide 3-kinase delta syndrome [APDS]
Related codes at this level
Codes that share D81.8. If D81.82 is not quite right, the correct code is usually one of these.
Questions about D81.82
- Is D81.82 a billable ICD-10-CM code?
- Yes. D81.82 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does D81.82 sit in the tabular list?
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Certain disorders involving the immune mechanism (D80-D89).