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E88.09

E88.09: Other disorders of plasma-protein metabolism, not elsewhere classified

Billable / specific codeICD-10-CM

E88.09 is a billable, specific ICD-10-CM code for other disorders of plasma-protein metabolism, not elsewhere classified. It is valid for submission on a claim.

Check E88.09 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Bisalbuminemia

Excludes1 inherited from the categories above E88.09

A category’s note binds every code beneath it.

Written on E88.0: Disorders of plasma-protein metabolism, not elsewhere classified

  • monoclonal gammopathy (of undetermined significance) (D47.2)
  • polyclonal hypergammaglobulinemia (D89.0)
  • Waldenström macroglobulinemia (C88.00)

Written on E88: Other and unspecified metabolic disorders

  • histiocytosis X (chronic) (C96.6)

Excludes2 inherited from the categories above E88.09

Not part of this code, but both may be coded when both are present.

Written on E88.0: Disorders of plasma-protein metabolism, not elsewhere classified

  • disorder of lipoprotein metabolism (E78.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

E88.09 is named in 3 Medicare coverage policies: 3 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A57689Billing and Coding: Lab: Flow Cytometry

Alphabetic index entries that lead here

  • Analbuminemia
  • Atransferrinemia, congenital
  • Bisalbuminemia
  • Dysproteinemia
  • Hyperproteinemia
  • Hypoalbuminemia
  • Para-albuminemia
  • Pyroglobulinemia NEC
  • Abnormal, abnormality, abnormalities›transport protein
  • Absence›albumin in blood
  • Deficiency, deficient›enzymes, circulating NEC
  • Deficiency, deficient›pseudocholinesterase

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E88.0

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.