E88.01 — Alpha-1-antitrypsin deficiency
E88.01 is a billable, specific ICD-10-CM code for alpha-1-antitrypsin deficiency. It is valid for submission on a claim.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- AAT deficiency
Risk adjustment
E88.01 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders0.648 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
E88.01 is named in 4 Medicare coverage policies — 4 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A56199Billing and Coding: Molecular Pathology Procedures
- A56717Billing and Coding: Respiratory Therapy (Respiratory Care)
- A57224Billing and Coding: Respiratory Care
- A60409Billing and Coding: Molecular Pathology Procedures
How E88.01 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E88.01.
- Deficiency, deficient›alpha-1-antitrypsin
- Deficiency, deficient›serum antitrypsin, familial
Related codes at this level
Codes that share E88.0. If E88.01 is not quite right, the correct code is usually one of these.
Questions about E88.01
- Is E88.01 a billable ICD-10-CM code?
- Yes. E88.01 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E88.01 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).