E88.01: Alpha-1-antitrypsin deficiency
E88.01 is a billable, specific ICD-10-CM code for alpha-1-antitrypsin deficiency. It is valid for submission on a claim.
Check E88.01 with the rest of the claim: free scrubberInclusion terms
Alternative wordings a physician may use in the chart for this same code.
- AAT deficiency
Excludes1 inherited from the categories above E88.01
A category’s note binds every code beneath it.
Written on E88.0: Disorders of plasma-protein metabolism, not elsewhere classified
Excludes2 inherited from the categories above E88.01
Not part of this code, but both may be coded when both are present.
Risk adjustment
E88.01 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders0.648 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.
Medicare coverage
E88.01 is named in 4 Medicare coverage policies: 4 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.
- A56199Billing and Coding: Molecular Pathology Procedures
- A56717Billing and Coding: Respiratory Therapy (Respiratory Care)
- A57224Billing and Coding: Respiratory Care
- A60409Billing and Coding: Molecular Pathology Procedures
Alphabetic index entries that lead here
- Deficiency, deficient›alpha-1-antitrypsin
- Deficiency, deficient›serum antitrypsin, familial
Code history
Unchanged in every release from FY2024 to FY2027.