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C88.00

C88.00: Waldenstrom macroglobulinemia not having achieved remission

Billable / specific codeICD-10-CM

C88.00 is a billable, specific ICD-10-CM code for waldenstrom macroglobulinemia not having achieved remission. It is valid for submission on a claim.

Check C88.00 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Lymphoplasmacytic lymphoma with IgM-production, NOS
  • Lymphoplasmacytic lymphoma with IgM-production not having achieved remission
  • Lymphoplasmacytic lymphoma with IgM-production with failed remission
  • Macroglobulinemia (idiopathic) (primary) NOS
  • Macroglobulinemia (idiopathic) (primary) not having achieved remission
  • Macroglobulinemia (idiopathic) (primary) with failed remission
  • Waldenström macroglobulinemia NOS
  • Waldenström macroglobulinemia with failed remission

Excludes1 inherited from the categories above C88.00

A category’s note binds every code beneath it.

Written on C88.0: Waldenstrom macroglobulinemia

  • small cell B-cell lymphoma (C83.0)

Written on C88: Malignant immunoproliferative diseases and certain other B-cell lymphomas

  • B-cell lymphoma, unspecified (C85.1-)
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Other codes that can never be billed with C88.00

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E88.0Disorders of plasma-protein metabolism, not elsewhere classified
  • C83.0Small cell B-cell lymphoma

Risk adjustment

C88.00 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 21 Lymphoma and Other Cancers0.671 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

C88.00 is named in 35 Medicare coverage policies: 35 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A52479Oral Anticancer Drugs - Policy Article
  • A52480Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
  • A52986Billing and Coding: Biomarkers for Oncology
  • A54768Billing and Coding: Cardiac Blood Pool Imaging (Multiple Gated Acquisition Scanning- MUGA, Ventriculography) When Performed in Conjunction with Cardiotoxic Chemotherapy

Code history

  • addedFY2024-FY2027

    Waldenstrom macroglobulinemia not having achieved remission

Other codes under C88.0

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.