MCMCB Pro
C88.0

C88.0Waldenstrom macroglobulinemia

Non-billable headerICD-10-CM

C88.0 is a non-billable header ICD-10-CM code for waldenstrom macroglobulinemia. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • small cell B-cell lymphoma (C83.0)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Lymphoplasmacytic lymphoma with IgM-production
  • Macroglobulinemia (idiopathic) (primary)

Other codes that can never be billed with C88.0

These codes carry an Excludes1 note pointing at C88.0. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C88.0 alone.

  • C83.0Small cell B-cell lymphoma
  • E88.0Disorders of plasma-protein metabolism, not elsewhere classified

Risk adjustment

C88.0 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

C88.0 is named in 2 Medicare coverage policies 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A59491Billing and Coding: Genetic Testing for Oncology
  • A59491Billing and Coding: Genetic Testing for Oncology

Code to one of these instead C88.0

2 child codes. Green means billable.

Related codes at this level

Codes that share C88. If C88.0 is not quite right, the correct code is usually one of these.

Questions about C88.0

Is C88.0 a billable ICD-10-CM code?
No. C88.0 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does C88.0 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96).
What cannot be coded together with C88.0?
C88.0 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.