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C88.0

C88.0: Waldenstrom macroglobulinemia

Non-billable headerICD-10-CM

C88.0 is a non-billable header ICD-10-CM code for waldenstrom macroglobulinemia. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • small cell B-cell lymphoma (C83.0)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Lymphoplasmacytic lymphoma with IgM-production
  • Macroglobulinemia (idiopathic) (primary)

Excludes1 inherited from the categories above C88.0

A category’s note binds every code beneath it.

Written on C88: Malignant immunoproliferative diseases and certain other B-cell lymphomas

  • B-cell lymphoma, unspecified (C85.1-)
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Other codes that can never be billed with C88.0

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E88.0Disorders of plasma-protein metabolism, not elsewhere classified
  • C83.0Small cell B-cell lymphoma

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

C88.0 is named in 1 Medicare coverage policy: 1 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A59491Billing and Coding: Genetic Testing for Oncology

Code history

  • deletedFY2024-FY2027

    Waldenstrom macroglobulinemia

Code to one of these instead C88.0

2 child codes. Green means billable.

Other codes under C88

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.