C88.0 — Waldenstrom macroglobulinemia
C88.0 is a non-billable header ICD-10-CM code for waldenstrom macroglobulinemia. It cannot be billed on its own: choose one of the more specific child codes below.
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
- small cell B-cell lymphoma (C83.0)
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Lymphoplasmacytic lymphoma with IgM-production
- Macroglobulinemia (idiopathic) (primary)
Excludes1 inherited from the categories above C88.0
These are not written on C88.0, but they bind it: a note on a category applies to every code beneath it. Billing C88.0 with anything listed here is a denial.
Other codes that can never be billed with C88.0
These codes carry an Excludes1 note pointing at C88.0. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C88.0 alone.
Risk adjustment
C88.0 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Medicare coverage
C88.0 is named in 2 Medicare coverage policies — 2 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A59491Billing and Coding: Genetic Testing for Oncology
- A59491Billing and Coding: Genetic Testing for Oncology
Code history
What changed, and when. Derived by diffing consecutive CMS release files — which matters when you are defending a code assigned under an earlier edition.
- deletedFY2024-FY2026
Waldenstrom macroglobulinemia
Code to one of these instead C88.0
2 child codes. Green means billable.
Related codes at this level
Codes that share C88. If C88.0 is not quite right, the correct code is usually one of these.
Questions about C88.0
- Is C88.0 a billable ICD-10-CM code?
- No. C88.0 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
- Where does C88.0 sit in the tabular list?
- Neoplasms (C00-D49), in the block Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96).
- What cannot be coded together with C88.0?
- C88.0 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above C88.0 (C88) and apply to it just the same.