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C88.2

C88.2: Heavy chain disease

Non-billable headerICD-10-CM

C88.2 is a non-billable header ICD-10-CM code for heavy chain disease. It cannot be billed on its own: choose one of the more specific child codes below.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Franklin disease
  • Gamma heavy chain disease
  • Mu heavy chain disease

Excludes1 inherited from the categories above C88.2

A category’s note binds every code beneath it.

Written on C88: Malignant immunoproliferative diseases and certain other B-cell lymphomas

  • B-cell lymphoma, unspecified (C85.1-)
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

C88.2 is named in 1 Medicare coverage policy: 1 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A59491Billing and Coding: Genetic Testing for Oncology

Code history

  • deletedFY2024-FY2027

    Heavy chain disease

Code to one of these instead C88.2

2 child codes. Green means billable.

Other codes under C88

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.