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C88

C88Malignant immunoproliferative diseases and certain other B-cell lymphomas

Non-billable headerICD-10-CM

C88 is a non-billable header ICD-10-CM code for malignant immunoproliferative diseases and certain other b-cell lymphomas. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • B-cell lymphoma, unspecified (C85.1-)
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Other codes that can never be billed with C88

These codes carry an Excludes1 note pointing at C88. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C88 alone.

  • C77Secondary and unspecified malignant neoplasm of lymph nodes
  • C83.0Small cell B-cell lymphoma
  • E88.0Disorders of plasma-protein metabolism, not elsewhere classified

Risk adjustment

C88 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead C88

6 child codes. Green means billable.

Questions about C88

Is C88 a billable ICD-10-CM code?
No. C88 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does C88 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96).
What cannot be coded together with C88?
C88 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.