Is C88.3 a billable ICD-10-CM code?

No. C88.3 is a non-billable header code. Code to a higher level of specificity using one of its child codes.

Where does C88.3 sit in the tabular list?

Neoplasms (C00-D49), in the block Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96).

What cannot be coded together with C88.3?

C88.3 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above C88.3 (C88) and apply to it just the same.

C88.3

C88.3 — Immunoproliferative small intestinal disease

Non-billable headerICD-10-CM

C88.3 is a non-billable header ICD-10-CM code for immunoproliferative small intestinal disease. It cannot be billed on its own: choose one of the more specific child codes below.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Alpha heavy chain disease
Mediterranean lymphoma

Excludes1 inherited from the categories above C88.3

These are not written on C88.3, but they bind it: a note on a category applies to every code beneath it. Billing C88.3 with anything listed here is a denial.

Written on C88 — Malignant immunoproliferative diseases and certain other B-cell lymphomas

B-cell lymphoma, unspecified (C85.1-)
personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Risk adjustment

C88.3 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

C88.3 is named in 1 Medicare coverage policy — 1 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

A59491Billing and Coding: Genetic Testing for Oncology

Code history

What changed, and when. Derived by diffing consecutive CMS release files — which matters when you are defending a code assigned under an earlier edition.

deletedFY2024-FY2026
Immunoproliferative small intestinal disease

Code to one of these instead C88.3

2 child codes. Green means billable.

Related codes at this level

Codes that share C88. If C88.3 is not quite right, the correct code is usually one of these.

Questions about C88.3

Is C88.3 a billable ICD-10-CM code?: No. C88.3 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does C88.3 sit in the tabular list?: Neoplasms (C00-D49), in the block Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96).
What cannot be coded together with C88.3?: C88.3 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above C88.3 (C88) and apply to it just the same.