Is E72.5 a billable ICD-10-CM code?

No. E72.5 is a non-billable header code. Code to a higher level of specificity using one of its child codes.

Where does E72.5 sit in the tabular list?

Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).

What cannot be coded together with E72.5?

E72.5 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E72.5 (E72) and apply to it just the same.

E72.5

E72.5 — Disorders of glycine metabolism

Non-billable headerICD-10-CM

E72.5 is a non-billable header ICD-10-CM code for disorders of glycine metabolism. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 inherited from the categories above E72.5

These are not written on E72.5, but they bind it: a note on a category applies to every code beneath it. Billing E72.5 with anything listed here is a denial.

Written on E72 — Other disorders of amino-acid metabolism

disorders of:
aromatic amino-acid metabolism (E70.-)
branched-chain amino-acid metabolism (E71.0-E71.2)
fatty-acid metabolism (E71.3)
purine and pyrimidine metabolism (E79.-)
gout (M1A.-, M10.-)

Other codes that can never be billed with E72.5

These codes carry an Excludes1 note pointing at E72.5. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E72.5 alone.

E72.53Primary hyperoxaluria
E72.54Secondary hyperoxaluria
R82.992Hyperoxaluria

Risk adjustment

E72.5 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code history

E72.5 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Code to one of these instead E72.5

6 child codes. Green means billable.

Related codes at this level

Codes that share E72. If E72.5 is not quite right, the correct code is usually one of these.

Questions about E72.5

Is E72.5 a billable ICD-10-CM code?: No. E72.5 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does E72.5 sit in the tabular list?: Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
What cannot be coded together with E72.5?: E72.5 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E72.5 (E72) and apply to it just the same.