MCMCB Pro
E72.53

E72.53Primary hyperoxaluria

Non-billable headerICD-10-CM

E72.53 is a non-billable header ICD-10-CM code for primary hyperoxaluria. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • secondary hyperoxaluria (E72.54-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Oxalosis
  • Oxaluria

Other codes that can never be billed with E72.53

These codes carry an Excludes1 note pointing at E72.53. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E72.53 alone.

Risk adjustment

E72.53 risk-adjusts. Under the CMS-HCC V28 model it maps to these categories:

  • HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders0.648 RAF
  • HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders0.648 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

How E72.53 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E72.53.

  • Oxalosis
  • Oxaluria
  • Hyperoxaluriaprimary
  • Disorderglycine metabolismoxalosis
  • Disorderglycine metabolismoxaluria
  • Disordermetabolism NOSamino-acidglycinehyperoxaluriaprimary

Code to one of these instead E72.53

3 child codes. Green means billable.

Related codes at this level

Codes that share E72.5. If E72.53 is not quite right, the correct code is usually one of these.

Questions about E72.53

Is E72.53 a billable ICD-10-CM code?
No. E72.53 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does E72.53 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
What cannot be coded together with E72.53?
E72.53 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.