E72.2

E72.2: Disorders of urea cycle metabolism

Non-billable headerICD-10-CM

E72.2 is a non-billable header ICD-10-CM code for disorders of urea cycle metabolism. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

disorders of ornithine metabolism (E72.4)

Excludes1 inherited from the categories above E72.2

A category’s note binds every code beneath it.

Written on E72: Other disorders of amino-acid metabolism

disorders of:
aromatic amino-acid metabolism (E70.-)
branched-chain amino-acid metabolism (E71.0-E71.2)
fatty-acid metabolism (E71.3)
purine and pyrimidine metabolism (E79.-)
gout (M1A.-, M10.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead E72.2

5 child codes. Green means billable.

E72.20Disorder of urea cycle metabolism, unspecified
E72.21Argininemia
E72.22Arginosuccinic aciduria
E72.23Citrullinemia
E72.29Other disorders of urea cycle metabolism

Other codes under E72

E72.0Disorders of amino-acid transport
E72.1Disorders of sulfur-bearing amino-acid metabolism
E72.3Disorders of lysine and hydroxylysine metabolism
E72.4Disorders of ornithine metabolism
E72.5Disorders of glycine metabolism
E72.8Other specified disorders of amino-acid metabolism
E72.9Disorder of amino-acid metabolism, unspecified