MCMedicalCodingSoftware
E72.4

E72.4: Disorders of ornithine metabolism

Billable / specific codeICD-10-CM

E72.4 is a billable, specific ICD-10-CM code for disorders of ornithine metabolism. It is valid for submission on a claim.

Check E72.4 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • hereditary choroidal dystrophy (H31.2-)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Hyperammonemia-Hyperornithinemia-Homocitrullinemia syndrome
  • Ornithinemia (types I, II)
  • Ornithine transcarbamylase deficiency

Excludes1 inherited from the categories above E72.4

A category’s note binds every code beneath it.

Written on E72: Other disorders of amino-acid metabolism

  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Other codes that can never be billed with E72.4

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • E72.2Disorders of urea cycle metabolism
  • E72.20Disorder of urea cycle metabolism, unspecified

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Alphabetic index entries that lead here

  • Hyperornithinemia
  • Ornithine metabolism disorder
  • Ornithinemia(Type I) (Type II)
  • Deficiency, deficient›ornithine transcarbamylase
  • Disorder›ornithine metabolism
  • Hyperaminoaciduria›ornithine
  • Syndrome›hyperammonemia-hyperornithinemia-homocitrullinemia
  • Disorder›metabolism NOS›ornithine
  • Disorder›urea cycle metabolism›ornithine transcarbamylase deficiency
  • Disturbance›metabolism›ornithine
  • Disorder›metabolism NOS›amino-acid›ornithine

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E72

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.