MCMedicalCodingSoftware
E72.20

E72.20: Disorder of urea cycle metabolism, unspecified

Billable / specific codeICD-10-CM

E72.20 is a billable, specific ICD-10-CM code for disorder of urea cycle metabolism, unspecified. It is valid for submission on a claim.

Check E72.20 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • hyperammonemia-hyperornithinemia-homocitrullinemia syndrome E72.4
  • transient hyperammonemia of newborn (P74.6)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Hyperammonemia

Excludes1 inherited from the categories above E72.20

A category’s note binds every code beneath it.

Written on E72.2: Disorders of urea cycle metabolism

  • disorders of ornithine metabolism (E72.4)

Written on E72: Other disorders of amino-acid metabolism

  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Alphabetic index entries that lead here

  • Hyperammonemia(congenital)
  • Disorder›urea cycle metabolism
  • Disturbance›metabolism›ammonia
  • Disturbance›metabolism›urea cycle

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under E72.2

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.