E72.20 — Disorder of urea cycle metabolism, unspecified
E72.20 is a billable, specific ICD-10-CM code for disorder of urea cycle metabolism, unspecified. It is valid for submission on a claim.
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Hyperammonemia
Excludes1 inherited from the categories above E72.20
These are not written on E72.20, but they bind it: a note on a category applies to every code beneath it. Billing E72.20 with anything listed here is a denial.
Risk adjustment
E72.20 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
How E72.20 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E72.20.
- Hyperammonemia(congenital)
- Disorder›urea cycle metabolism
- Disturbance›metabolism›ammonia
- Disturbance›metabolism›urea cycle
Code history
E72.20 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.
Related codes at this level
Codes that share E72.2. If E72.20 is not quite right, the correct code is usually one of these.
Questions about E72.20
- Is E72.20 a billable ICD-10-CM code?
- Yes. E72.20 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E72.20 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
- What cannot be coded together with E72.20?
- E72.20 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above E72.20 (E72.2, E72) and apply to it just the same.