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D57.458

D57.458: Sickle-cell thalassemia beta plus with crisis with other specified complication

Billable / specific codeICD-10-CM

D57.458 is a billable, specific ICD-10-CM code for sickle-cell thalassemia beta plus with crisis with other specified complication. It is valid for submission on a claim.

Check D57.458 with the rest of the claim: free scrubber

Use additional code

Add a secondary code to capture the detail described below.

  • code to identify complications, such as:
  • cholelithiasis (K80.-)
  • priapism (N48.32)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • HbS-beta plus with crisis with other specified complication
  • Sickle-cell beta plus with crisis with other specified complication

Excludes1 inherited from the categories above D57.458

A category’s note binds every code beneath it.

Written on D57: Sickle-cell disorders

  • other hemoglobinopathies (D58.-)

Other codes that can never be billed with D57.458

Their own Excludes1 notes name this code, so the conflict is not listed above.

Risk adjustment

D57.458 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 108 Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major0.146 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D57.458 is named in 14 Medicare coverage policies: 14 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56464Billing and Coding: Flow Cytometry
  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax

Alphabetic index entries that lead here

  • Disease, diseased›sickle-cell›thalassemia›beta plus›with›priapism
  • Disease, diseased›sickle-cell›thalassemia›beta plus›with›crisis›with specified complication NEC
  • Disease, diseased›hemoglobin or Hb›S or SS›beta plus›with›crisis›with›specified complication

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D57.45

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.