D57.453 — Sickle-cell thalassemia beta plus with cerebral vascular involvement
D57.453 is a billable, specific ICD-10-CM code for sickle-cell thalassemia beta plus with cerebral vascular involvement. It is valid for submission on a claim.
Code also
Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.
- , if applicable cerebral infarction (I63.-)
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- HbS-beta plus with cerebral vascular involvement
- Sickle-cell beta plus with cerebral vascular involvement
Risk adjustment
D57.453 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 108 Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major0.146 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.
Medicare coverage
D57.453 is named in 12 Medicare coverage policies — 12 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A55717Billing and Coding: Lab: Flow Cytometry
- A56464Billing and Coding: Flow Cytometry
- A56697Billing and Coding: Non-Invasive Vascular Studies
- A56758Billing and Coding: Non-Invasive Vascular Studies
How D57.453 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D57.453.
- Disease, diseased›hemoglobin or Hb›S or SS›beta plus›with›cerebral vascular involvement
- Disease, diseased›sickle-cell›thalassemia›beta plus›with›cerebral vascular involvement
Related codes at this level
Codes that share D57.45. If D57.453 is not quite right, the correct code is usually one of these.
- D57.451Sickle-cell thalassemia beta plus with acute chest syndrome
- D57.452Sickle-cell thalassemia beta plus with splenic sequestration
- D57.454Sickle-cell thalassemia beta plus with dactylitis
- D57.458Sickle-cell thalassemia beta plus with crisis with other specified complication
- D57.459Sickle-cell thalassemia beta plus with crisis, unspecified
Questions about D57.453
- Is D57.453 a billable ICD-10-CM code?
- Yes. D57.453 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does D57.453 sit in the tabular list?
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).