D57.453: Sickle-cell thalassemia beta plus with cerebral vascular involvement
D57.453 is a billable, specific ICD-10-CM code for sickle-cell thalassemia beta plus with cerebral vascular involvement. It is valid for submission on a claim.
Check D57.453 with the rest of the claim: free scrubberCode also
Both codes may be needed to describe the encounter fully. Sequencing depends on the reason for the visit.
- , if applicable cerebral infarction (I63.-)
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- HbS-beta plus with cerebral vascular involvement
- Sickle-cell beta plus with cerebral vascular involvement
Other codes that can never be billed with D57.453
Their own Excludes1 notes name this code, so the conflict is not listed above.
- D56.8Other thalassemias
Risk adjustment
D57.453 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:
- HCC 108 Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major0.146 RAF
Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.
Medicare coverage
D57.453 is named in 12 Medicare coverage policies: 12 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.
- A55717Billing and Coding: Lab: Flow Cytometry
- A56464Billing and Coding: Flow Cytometry
- A56697Billing and Coding: Non-Invasive Vascular Studies
- A56758Billing and Coding: Non-Invasive Vascular Studies
Alphabetic index entries that lead here
- Disease, diseased›hemoglobin or Hb›S or SS›beta plus›with›cerebral vascular involvement
- Disease, diseased›sickle-cell›thalassemia›beta plus›with›cerebral vascular involvement
Code history
Unchanged in every release from FY2024 to FY2027.
Other codes under D57.45
- D57.451Sickle-cell thalassemia beta plus with acute chest syndrome
- D57.452Sickle-cell thalassemia beta plus with splenic sequestration
- D57.454Sickle-cell thalassemia beta plus with dactylitis
- D57.458Sickle-cell thalassemia beta plus with crisis with other specified complication
- D57.459Sickle-cell thalassemia beta plus with crisis, unspecified