MCMCB Pro
D57

D57Sickle-cell disorders

Non-billable headerICD-10-CM

D57 is a non-billable header ICD-10-CM code for sickle-cell disorders. It cannot be billed on its own: choose one of the more specific child codes below.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • other hemoglobinopathies (D58.-)

Use additional code

Add a secondary code to capture the detail described below.

  • code for any associated fever (R50.81)

Other codes that can never be billed with D57

These codes carry an Excludes1 note pointing at D57. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D57 alone.

Risk adjustment

D57 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Code to one of these instead D57

6 child codes. Green means billable.

Questions about D57

Is D57 a billable ICD-10-CM code?
No. D57 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does D57 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
What cannot be coded together with D57?
D57 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.