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D56.3

D56.3: Thalassemia minor

Billable / specific codeICD-10-CM

D56.3 is a billable, specific ICD-10-CM code for thalassemia minor. It is valid for submission on a claim.

Check D56.3 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • alpha thalassemia (D56.0)
  • beta thalassemia (D56.1)
  • delta-beta thalassemia (D56.2)
  • hemoglobin E-beta thalassemia (D56.5)
  • sickle-cell trait (D57.3)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Alpha thalassemia minor
  • Alpha thalassemia silent carrier
  • Alpha thalassemia trait
  • Beta thalassemia minor
  • Beta thalassemia trait
  • Delta-beta thalassemia minor
  • Delta-beta thalassemia trait
  • Thalassemia trait NOS

Excludes1 inherited from the categories above D56.3

A category’s note binds every code beneath it.

Written on D56: Thalassemia

  • sickle-cell thalassemia (D57.4-)

Other codes that can never be billed with D56.3

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • D56.0Alpha thalassemia
  • D56.1Beta thalassemia
  • D56.2Delta-beta thalassemia
  • D56.5Hemoglobin E-beta thalassemia

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D56.3 is named in 10 Medicare coverage policies: 10 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax
  • A56697Billing and Coding: Non-Invasive Vascular Studies

Alphabetic index entries that lead here

  • Thalassemia›minor
  • Thalassemia›trait
  • Trait›Lepore
  • Thalassemia›alpha›minor
  • Thalassemia›alpha›silent carrier
  • Thalassemia›alpha›trait
  • Thalassemia›beta›minor
  • Thalassemia›beta›trait
  • Thalassemia›delta-beta›minor
  • Thalassemia›delta-beta›trait
  • Trait›hemoglobin›abnormal NEC›with thalassemia

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D56

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.