MCMedicalCodingSoftware
D56.0

D56.0: Alpha thalassemia

Billable / specific codeICD-10-CM

D56.0 is a billable, specific ICD-10-CM code for alpha thalassemia. It is valid for submission on a claim.

Check D56.0 with the rest of the claim: free scrubber

Excludes1: never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • alpha thalassemia trait or minor (D56.3)
  • asymptomatic alpha thalassemia (D56.3)
  • hydrops fetalis due to isoimmunization (P56.0)
  • hydrops fetalis not due to immune hemolysis (P83.2)

Use additional code

Add a secondary code to capture the detail described below.

  • code, if applicable, for hydrops fetalis due to alpha thalassemia (P56.99)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Alpha thalassemia major
  • Hemoglobin H Constant Spring
  • Hemoglobin H disease
  • Hydrops fetalis due to alpha thalassemia
  • Severe alpha thalassemia
  • Triple gene defect alpha thalassemia

Excludes1 inherited from the categories above D56.0

A category’s note binds every code beneath it.

Written on D56: Thalassemia

  • sickle-cell thalassemia (D57.4-)

Other codes that can never be billed with D56.0

Their own Excludes1 notes name this code, so the conflict is not listed above.

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D56.0 is named in 10 Medicare coverage policies: 10 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax
  • A56697Billing and Coding: Non-Invasive Vascular Studies

Alphabetic index entries that lead here

  • Hb›Bart's disease
  • Hemoglobin›H Constant Spring
  • Thalassemia›alpha(major) (severe) (triple gene defect)
  • Disease, diseased›hemoglobin or Hb›Bart's
  • Disease, diseased›hemoglobin or Hb›H(Hb-H) (thalassemia)
  • Disease, diseased›hemoglobin or Hb›H›Constant Spring
  • Hydrops›fetalis›due to›alpha thalassemia
  • Hydrops›newborn›due to›alpha thalassemia

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D56

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.