D57.3 — Sickle-cell trait
D57.3 is a billable, specific ICD-10-CM code for sickle-cell trait. It is valid for submission on a claim.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Hb-S trait
- Heterozygous hemoglobin S
Other codes that can never be billed with D57.3
These codes carry an Excludes1 note pointing at D57.3. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading D57.3 alone.
- D56.3Thalassemia minor
Risk adjustment
D57.3 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Medicare coverage
D57.3 is named in 8 Medicare coverage policies — 8 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A55717Billing and Coding: Lab: Flow Cytometry
- A56464Billing and Coding: Flow Cytometry
- A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)
- A57110Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
How D57.3 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D57.3.
- Hemoglobin›AS genotype
- Hemoglobin›S, heterozygous(Hb S)
- Sickle-cell›trait
- Sicklemia›trait
- Trait›Hb-S
- Trait›sickle-cell
- Disease, diseased›hemoglobin or Hb›AS genotype
- Disorder›sickle-cell›heterozygous
- Disorder›sickle-cell›trait
- Elliptocytosis›sickle-cell›trait
- Trait›hemoglobin›S(Hb-S)
- Trait›sickle-cell›with elliptocytosis or spherocytosis
Related codes at this level
Codes that share D57. If D57.3 is not quite right, the correct code is usually one of these.
Questions about D57.3
- Is D57.3 a billable ICD-10-CM code?
- Yes. D57.3 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does D57.3 sit in the tabular list?
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).