MCMedicalCodingSoftware
D57.3

D57.3: Sickle-cell trait

Billable / specific codeICD-10-CM

D57.3 is a billable, specific ICD-10-CM code for sickle-cell trait. It is valid for submission on a claim.

Check D57.3 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Hb-S trait
  • Heterozygous hemoglobin S

Excludes1 inherited from the categories above D57.3

A category’s note binds every code beneath it.

Written on D57: Sickle-cell disorders

  • other hemoglobinopathies (D58.-)

Other codes that can never be billed with D57.3

Their own Excludes1 notes name this code, so the conflict is not listed above.

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

D57.3 is named in 8 Medicare coverage policies: 8 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A55717Billing and Coding: Lab: Flow Cytometry
  • A56464Billing and Coding: Flow Cytometry
  • A56718Billing and Coding: Intravenous Immunoglobulin (IVIG)
  • A57110Billing and Coding: MolDX: Blood Product Molecular Antigen Typing

Alphabetic index entries that lead here

  • Hemoglobin›AS genotype
  • Hemoglobin›S, heterozygous(Hb S)
  • Sickle-cell›trait
  • Sicklemia›trait
  • Trait›Hb-S
  • Trait›sickle-cell
  • Disease, diseased›hemoglobin or Hb›AS genotype
  • Disorder›sickle-cell›heterozygous
  • Disorder›sickle-cell›trait
  • Elliptocytosis›sickle-cell›trait
  • Trait›hemoglobin›S(Hb-S)
  • Trait›sickle-cell›with elliptocytosis or spherocytosis

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D57

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.