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D57.419

D57.419: Sickle-cell thalassemia, unspecified, with crisis

Billable / specific codeICD-10-CM

D57.419 is a billable, specific ICD-10-CM code for sickle-cell thalassemia, unspecified, with crisis. It is valid for submission on a claim.

Check D57.419 with the rest of the claim: free scrubber

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Sickle-cell thalassemia with (painful) crisis NOS
  • Sickle-cell thalassemia with (vaso-occlusive) pain NOS

Excludes1 inherited from the categories above D57.419

A category’s note binds every code beneath it.

Written on D57: Sickle-cell disorders

  • other hemoglobinopathies (D58.-)

Other codes that can never be billed with D57.419

Their own Excludes1 notes name this code, so the conflict is not listed above.

Risk adjustment

D57.419 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 108 Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major0.146 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score. Look up the whole chart to see which of its HCCs the hierarchy would zero.

Medicare coverage

D57.419 is named in 6 Medicare coverage policies: 6 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax
  • A57110Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
  • A57124Billing and Coding: MolDX: Blood Product Molecular Antigen Typing
  • A57155Billing and Coding: MolDX: Blood Product Molecular Antigen Typing

Alphabetic index entries that lead here

  • Microdrepanocytosis›with›crisis(painful)
  • Microdrepanocytosis›with›pain(vaso-occlusive)
  • Disease, diseased›sickle-cell›thalassemia›with›crisis(painful)
  • Disease, diseased›sickle-cell›thalassemia›with›pain(vaso-occlusive)
  • Hemoglobinopathy›sickle-cell›with thalassemia›with›crisis(painful)
  • Hemoglobinopathy›sickle-cell›with thalassemia›with›pain(vaso-occlusive)

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under D57.41

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.