MCMCB Pro
D57.411

D57.411Sickle-cell thalassemia, unspecified, with acute chest syndrome

Billable / specific codeICD-10-CM

D57.411 is a billable, specific ICD-10-CM code for sickle-cell thalassemia, unspecified, with acute chest syndrome. It is valid for submission on a claim.

Risk adjustment

D57.411 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 108 Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major0.146 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

D57.411 is named in 12 Medicare coverage policies 12 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56580Billing and Coding: Computerized Axial Tomography (CT), Thorax
  • A56697Billing and Coding: Non-Invasive Vascular Studies
  • A56717Billing and Coding: Respiratory Therapy (Respiratory Care)

How D57.411 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to D57.411.

  • Microdrepanocytosiswithacute chest syndrome
  • Disease, diseasedsickle-cellthalassemiawithacute chest syndrome
  • Hemoglobinopathysickle-cellwith thalassemiawithacute chest syndrome

Related codes at this level

Codes that share D57.41. If D57.411 is not quite right, the correct code is usually one of these.

Questions about D57.411

Is D57.411 a billable ICD-10-CM code?
Yes. D57.411 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does D57.411 sit in the tabular list?
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89), in the block Hemolytic anemias (D55-D59).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.