Is Z16.35 a billable ICD-10-CM code?

Yes. Z16.35 is a billable, specific ICD-10-CM code and is valid for submission on a claim.

Where does Z16.35 sit in the tabular list?

Factors influencing health status and contact with health services (Z00-Z99), in the block Resistance to antimicrobial drugs (Z16).

What cannot be coded together with Z16.35?

Z16.35 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.

Z16.35

Z16.35 — Resistance to multiple antimicrobial drugs

Billable / specific codeICD-10-CM

Z16.35 is a billable, specific ICD-10-CM code for resistance to multiple antimicrobial drugs. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

Resistance to multiple antibiotics only (Z16.24)

Risk adjustment

Z16.35 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How Z16.35 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to Z16.35.

Resistance, resistant›organism›to›drug›antimicrobial›multiple
Resistance, resistant›organism›to›drug›multiple drugs›antimicrobial

Related codes at this level

Codes that share Z16.3. If Z16.35 is not quite right, the correct code is usually one of these.

Questions about Z16.35

Is Z16.35 a billable ICD-10-CM code?: Yes. Z16.35 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does Z16.35 sit in the tabular list?: Factors influencing health status and contact with health services (Z00-Z99), in the block Resistance to antimicrobial drugs (Z16).
What cannot be coded together with Z16.35?: Z16.35 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.