MCMCB Pro
Z16.342

Z16.342Resistance to multiple antimycobacterial drugs

Billable / specific codeICD-10-CM

Z16.342 is a billable, specific ICD-10-CM code for resistance to multiple antimycobacterial drugs. It is valid for submission on a claim.

Risk adjustment

Z16.342 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How Z16.342 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to Z16.342.

  • Resistance, resistantorganismtodrugantimycobacterialmultiple
  • Resistance, resistantorganismtodrugmultiple drugsantimycobacterials
  • Resistance, resistantorganismtodrugtuberculostaticsmultiple

Related codes at this level

Codes that share Z16.34. If Z16.342 is not quite right, the correct code is usually one of these.

Questions about Z16.342

Is Z16.342 a billable ICD-10-CM code?
Yes. Z16.342 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does Z16.342 sit in the tabular list?
Factors influencing health status and contact with health services (Z00-Z99), in the block Resistance to antimicrobial drugs (Z16).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.