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T88.6XXD

T88.6XXDAnaphylactic reaction due to adverse effect of correct drug or medicament properly administered, subsequent encounter

Billable / specific codeICD-10-CMPOA exempt

T88.6XXD is a billable, specific ICD-10-CM code for anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, subsequent encounter. It is valid for submission on a claim.

7th character "D" — subsequent encounter

The appropriate 7th character is to be added to each code from category T88

A
initial encounter
D
subsequent encounter
S
sequela

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • anaphylactic reaction due to serum (T80.5-)
  • anaphylactic shock or reaction due to adverse food reaction (T78.0-)

Use additional code

Add a secondary code to capture the detail described below.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
  • Anaphylactoid reaction NOS

Excludes1 inherited from the categories above T88.6XXD

These are not written on T88.6XXD, but they bind it: a note on a category applies to every code beneath it. Billing T88.6XXD with anything listed here is a denial.

Written on T88.6 Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered

  • anaphylactic reaction due to serum (T80.5-)
  • anaphylactic shock or reaction due to adverse food reaction (T78.0-)

Excludes2 inherited from the categories above T88.6XXD

Also inherited, and the opposite of Excludes1: these conditions are not part of T88.6XXD, but a patient can have both, so you may code both.

Written on T88 Other complications of surgical and medical care, not elsewhere classified

  • complication following infusion, transfusion and therapeutic injection (T80.-)
  • complication following procedure NEC (T81.-)
  • complications of anesthesia in labor and delivery (O74.-)
  • complications of anesthesia in pregnancy (O29.-)
  • complications of anesthesia in puerperium (O89.-)
  • complications of devices, implants and grafts (T82-T85)
  • complications of obstetric surgery and procedure (O75.4)
  • dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
  • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4)
  • specified complications classified elsewhere

Risk adjustment

T88.6XXD does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

T88.6XXD is named in 18 Medicare coverage policies 18 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A53065Billing and Coding: Outpatient Physical Therapy
  • A56559Billing and Coding: Allergy Skin Testing
  • A56559Billing and Coding: Allergy Skin Testing
  • A56625Billing and Coding: Echocardiography

Code history

T88.6XXD has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share T88.6. If T88.6XXD is not quite right, the correct code is usually one of these.

Questions about T88.6XXD

Is T88.6XXD a billable ICD-10-CM code?
Yes. T88.6XXD is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does T88.6XXD sit in the tabular list?
Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
What cannot be coded together with T88.6XXD?
T88.6XXD carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above T88.6XXD (T88.6) and apply to it just the same.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.