Is T88.6 a billable ICD-10-CM code?

No. T88.6 is a non-billable header code. Code to a higher level of specificity using one of its child codes.

Where does T88.6 sit in the tabular list?

Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).

What cannot be coded together with T88.6?

T88.6 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter.

T88.6

T88.6 — Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered

Non-billable headerICD-10-CM

T88.6 is a non-billable header ICD-10-CM code for anaphylactic reaction due to adverse effect of correct drug or medicament properly administered. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.

This code requires a 7th character

The appropriate 7th character is to be added to each code from category T88

A: initial encounter
D: subsequent encounter
S: sequela

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

anaphylactic reaction due to serum (T80.5-)
anaphylactic shock or reaction due to adverse food reaction (T78.0-)

Use additional code

Add a secondary code to capture the detail described below.

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
Anaphylactoid reaction NOS

Excludes2 inherited from the categories above T88.6

Also inherited, and the opposite of Excludes1: these conditions are not part of T88.6, but a patient can have both, so you may code both.

Written on T88 — Other complications of surgical and medical care, not elsewhere classified

complication following infusion, transfusion and therapeutic injection (T80.-)
complication following procedure NEC (T81.-)
complications of anesthesia in labor and delivery (O74.-)
complications of anesthesia in pregnancy (O29.-)
complications of anesthesia in puerperium (O89.-)
complications of devices, implants and grafts (T82-T85)
complications of obstetric surgery and procedure (O75.4)
dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4)
specified complications classified elsewhere

Other codes that can never be billed with T88.6

These codes carry an Excludes1 note pointing at T88.6. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading T88.6 alone.

R57Shock, not elsewhere classified
T78.2Anaphylactic shock, unspecified
T78.2XXAAnaphylactic shock, unspecified, initial encounter
T78.2XXDAnaphylactic shock, unspecified, subsequent encounter
T78.2XXSAnaphylactic shock, unspecified, sequela
T79.4Traumatic shock
T79.4XXATraumatic shock, initial encounter
T79.4XXDTraumatic shock, subsequent encounter

Risk adjustment

T88.6 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

How T88.6 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to T88.6.

Shock›drug›due to correct substance properly administered
Allergy, allergic›shock›due to›adverse effect of correct medicinal substance properly administered
Shock›anaphylactic›due to drug or medicinal substance›correct substance properly administered

Code history

T88.6 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Code to one of these instead T88.6

3 child codes. Green means billable.

Related codes at this level

Codes that share T88. If T88.6 is not quite right, the correct code is usually one of these.

Questions about T88.6

Is T88.6 a billable ICD-10-CM code?: No. T88.6 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
Where does T88.6 sit in the tabular list?: Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
What cannot be coded together with T88.6?: T88.6 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter.