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L27.1

L27.1: Localized skin eruption due to drugs and medicaments taken internally

Billable / specific codeICD-10-CM

L27.1 is a billable, specific ICD-10-CM code for localized skin eruption due to drugs and medicaments taken internally. It is valid for submission on a claim.

Check L27.1 with the rest of the claim: free scrubber

Use additional code

Add a secondary code to capture the detail described below.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Excludes1 inherited from the categories above L27.1

A category’s note binds every code beneath it.

Written on L27: Dermatitis due to substances taken internally

Excludes2 inherited from the categories above L27.1

Not part of this code, but both may be coded when both are present.

Written on L27: Dermatitis due to substances taken internally

  • adverse food reaction, except dermatitis (T78.0-T78.1)
  • contact dermatitis (L23-L25)
  • drug photoallergic response (L56.1)
  • drug phototoxic response (L56.0)
  • urticaria (L50.-)

Other codes that can never be billed with L27.1

Their own Excludes1 notes name this code, so the conflict is not listed above.

  • T78.4Other and unspecified allergy

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Medicare coverage

L27.1 is named in 10 Medicare coverage policies: 10 listing it as supporting medical necessity. Which one applies depends on your Medicare contractor.

  • A60360Billing and Coding: Allergy Diagnostic Testing
  • A60361Billing and Coding: Allergy Diagnostic Testing
  • A60363Billing and Coding: Allergy Diagnostic Testing
  • A60364Billing and Coding: Allergy Diagnostic Testing

Alphabetic index entries that lead here

  • Erythrodysesthesia, palmar plantar(PPE)
  • Hand-foot syndrome
  • Syndrome›hand-foot
  • Eruption›drug›fixed
  • Eruption›drug›localized
  • Dermatitis›due to›drugs and medicaments›localized skin eruption
  • Eruption›skin›due to inoculation/vaccination›localized

Code history

Unchanged in every release from FY2024 to FY2027.

Other codes under L27

ICD-10-CMFY2027· effective October 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release: see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.