MCMCB Pro
T88.6XXA

T88.6XXAAnaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter

Billable / specific codeICD-10-CM

T88.6XXA is a billable, specific ICD-10-CM code for anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter. It is valid for submission on a claim.

7th character "A" — initial encounter

The appropriate 7th character is to be added to each code from category T88

A
initial encounter
D
subsequent encounter
S
sequela

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • anaphylactic reaction due to serum (T80.5-)
  • anaphylactic shock or reaction due to adverse food reaction (T78.0-)

Use additional code

Add a secondary code to capture the detail described below.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
  • Anaphylactoid reaction NOS

Risk adjustment

T88.6XXA does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

T88.6XXA is named in 14 Medicare coverage policies 14 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56730Billing and Coding: Respiratory Therapy and Oximetry Services
  • A56844Billing and Coding: RAST Type Tests
  • A57043Billing and Coding: RAST Type Tests
  • A57181Billing and Coding: Allergy Testing

Related codes at this level

Codes that share T88.6. If T88.6XXA is not quite right, the correct code is usually one of these.

Questions about T88.6XXA

Is T88.6XXA a billable ICD-10-CM code?
Yes. T88.6XXA is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does T88.6XXA sit in the tabular list?
Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
What cannot be coded together with T88.6XXA?
T88.6XXA carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.