T80.5 — Anaphylactic reaction due to serum
T80.5 is a non-billable header ICD-10-CM code for anaphylactic reaction due to serum. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.
This code requires a 7th character
The appropriate 7th character is to be added to each code from category T80
- A
- initial encounter
- D
- subsequent encounter
- S
- sequela
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
- ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
- allergic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
- other serum reaction (T80.6-)
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Allergic shock due to serum
- Anaphylactic shock due to serum
- Anaphylactoid reaction due to serum
- Anaphylaxis due to serum
Other codes that can never be billed with T80.5
These codes carry an Excludes1 note pointing at T80.5. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading T80.5 alone.
- R57Shock, not elsewhere classified
- T78.2Anaphylactic shock, unspecified
- T78.2XXAAnaphylactic shock, unspecified, initial encounter
- T78.2XXDAnaphylactic shock, unspecified, subsequent encounter
- T78.2XXSAnaphylactic shock, unspecified, sequela
- T79.4Traumatic shock
- T79.4XXATraumatic shock, initial encounter
- T79.4XXDTraumatic shock, subsequent encounter
Risk adjustment
T80.5 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Code to one of these instead T80.5
3 child codes. Green means billable.
Related codes at this level
Codes that share T80. If T80.5 is not quite right, the correct code is usually one of these.
- T80.0Air embolism following infusion, transfusion and therapeutic injection
- T80.1Vascular complications following infusion, transfusion and therapeutic injection
- T80.2Infections following infusion, transfusion and therapeutic injection
- T80.3ABO incompatibility reaction due to transfusion of blood or blood products
- T80.4Rh incompatibility reaction due to transfusion of blood or blood products
- T80.ANon-ABO incompatibility reaction due to transfusion of blood or blood products
- T80.6Other serum reactions
- T80.8Other complications following infusion, transfusion and therapeutic injection
- T80.9Unspecified complication following infusion, transfusion and therapeutic injection
Questions about T80.5
- Is T80.5 a billable ICD-10-CM code?
- No. T80.5 is a non-billable header code. Code to a higher level of specificity using one of its child codes.
- Where does T80.5 sit in the tabular list?
- Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
- What cannot be coded together with T80.5?
- T80.5 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.