T80.6

T80.6: Other serum reactions

Non-billable headerICD-10-CM

T80.6 is a non-billable header ICD-10-CM code for other serum reactions. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.

This code requires a 7th character

The appropriate 7th character is to be added to each code from category T80

A: initial encounter
D: subsequent encounter
S: sequela

Excludes2: not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

serum hepatitis (B16-B19)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

Intoxication by serum
Protein sickness
Serum rash
Serum sickness
Serum urticaria

Excludes2 inherited from the categories above T80.6

Not part of this code, but both may be coded when both are present.

Written on T80: Complications following infusion, transfusion and therapeutic injection

bone marrow transplant rejection (T86.01)
febrile nonhemolytic transfusion reaction (R50.84)
fluid overload due to transfusion (E87.71)
posttransfusion purpura (D69.51)
transfusion associated circulatory overload (TACO) (E87.71)
transfusion (red blood cell) associated hemochromatosis (E83.111)
transfusion related acute lung injury (TRALI) (J95.84)

Other codes that can never be billed with T80.6

Their own Excludes1 notes name this code, so the conflict is not listed above.

L50Urticaria
L95Vasculitis limited to skin, not elsewhere classified
T78.3Angioneurotic edema
T78.3XXAAngioneurotic edema, initial encounter
T78.3XXDAngioneurotic edema, subsequent encounter
T78.3XXSAngioneurotic edema, sequela
T80.5Anaphylactic reaction due to serum

Risk adjustment

No CMS-HCC V28 category: this code does not change a RAF score.

Code history

Unchanged in every release from FY2024 to FY2027.

Code to one of these instead T80.6

3 child codes. Green means billable.