T80.59
T80.59: Anaphylactic reaction due to other serum
Non-billable headerICD-10-CM
T80.59 is a non-billable header ICD-10-CM code for anaphylactic reaction due to other serum. It cannot be billed on its own: choose one of the more specific child codes below. This code also requires a 7th character before it is complete.
This code requires a 7th character
The appropriate 7th character is to be added to each code from category T80
- A
- initial encounter
- D
- subsequent encounter
- S
- sequela
Excludes1 inherited from the categories above T80.59
A category’s note binds every code beneath it.
Written on T80.5: Anaphylactic reaction due to serum
- ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
- allergic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
- other serum reaction (T80.6-)
Excludes2 inherited from the categories above T80.59
Not part of this code, but both may be coded when both are present.
Written on T80: Complications following infusion, transfusion and therapeutic injection
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
Risk adjustment
No CMS-HCC V28 category: this code does not change a RAF score.
Alphabetic index entries that lead here
- Allergy, allergic›serum›anaphylactic shock
- Reaction›serum›anaphylactic(immediate)
- Serum›allergy, allergic reaction›shock
- Shock›anaphylactic›serum
- Allergy, allergic›shock›due to›serum NEC
- Complication›infusion›serum reaction›anaphylactic shock
- Shock›anaphylactic›serum›specified NEC
Code history
Unchanged in every release from FY2024 to FY2027.
Code to one of these instead T80.59
3 child codes. Green means billable.