MCMCB Pro
T80.59XA

T80.59XAAnaphylactic reaction due to other serum, initial encounter

Billable / specific codeICD-10-CM

T80.59XA is a billable, specific ICD-10-CM code for anaphylactic reaction due to other serum, initial encounter. It is valid for submission on a claim.

7th character "A" — initial encounter

The appropriate 7th character is to be added to each code from category T80

A
initial encounter
D
subsequent encounter
S
sequela

Risk adjustment

T80.59XA does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

T80.59XA is named in 9 Medicare coverage policies 9 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56538Billing and Coding: Allergen Immunotherapy
  • A56558Billing and Coding: Allergy Testing
  • A56612Billing and Coding: CT of the Head
  • A56781Billing and Coding: Transthoracic Echocardiography (TTE)

Related codes at this level

Codes that share T80.59. If T80.59XA is not quite right, the correct code is usually one of these.

Questions about T80.59XA

Is T80.59XA a billable ICD-10-CM code?
Yes. T80.59XA is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does T80.59XA sit in the tabular list?
Injury, poisoning and certain other consequences of external causes (S00-T88), in the block Complications of surgical and medical care, not elsewhere classified (T80-T88).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.