MCMCB Pro
E88.89

E88.89Other specified metabolic disorders

Billable / specific codeICD-10-CM

E88.89 is a billable, specific ICD-10-CM code for other specified metabolic disorders. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • adult pulmonary Langerhans cell histiocytosis (J84.82)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Launois-Bensaude adenolipomatosis

Risk adjustment

E88.89 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders0.648 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

E88.89 is named in 7 Medicare coverage policies 7 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A56421Billing and Coding: CT of the Abdomen and Pelvis
  • A56943Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
  • A57037Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
  • A57224Billing and Coding: Respiratory Care

How E88.89 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E88.89.

  • Adenolipomatosis, Launois-Bensaude
  • Dihydropyrimidine dehydrogenase disease(DPD)
  • DPD(dihydropyrimidine dehydrogenase deficiency)
  • Hoffa-Kastert disease
  • Hoffa's disease
  • Ketosis NEC
  • Launois-Bensaude adenolipomatosis
  • Liposynovitis prepatellaris
  • Steatosis
  • Deficiency, deficientdihydropyrimidine dehydrogenase(DPD)
  • Disease, diseasedErdheim-Chester(ECD)
  • LipomatosisLaunois-Bensaude

Related codes at this level

Codes that share E88.8. If E88.89 is not quite right, the correct code is usually one of these.

Questions about E88.89

Is E88.89 a billable ICD-10-CM code?
Yes. E88.89 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E88.89 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
What cannot be coded together with E88.89?
E88.89 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.