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E85.1

E85.1Neuropathic heredofamilial amyloidosis

Billable / specific codeICD-10-CM

E85.1 is a billable, specific ICD-10-CM code for neuropathic heredofamilial amyloidosis. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Amyloid polyneuropathy (Portuguese)
  • Transthyretin-related (ATTR) familial amyloid polyneuropathy

Risk adjustment

E85.1 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 50 Amyloidosis, Porphyria, and Other Specified Metabolic Disorders0.648 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

E85.1 is named in 37 Medicare coverage policies 37 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52850Billing and Coding: Cardiac Catheterization and Coronary Angiography
  • A52850Billing and Coding: Cardiac Catheterization and Coronary Angiography
  • A52996Billing and Coding: Routine Foot Care
  • A54095Billing and Coding: Nerve Conduction Studies and Electromyography

How E85.1 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E85.1.

  • Amyloidosisneuropathic heredofamilial
  • AmyloidosisPortuguese
  • Polyneuropathyamyloid(Portuguese)
  • Polyneuropathyamyloidtransthyretin-related familial(ATTR)
  • Polyneuropathyinamyloidosis, familial(Portuguese)
  • Polyneuropathyintransthyretin-related familial amyloid(ATTR)

Related codes at this level

Codes that share E85. If E85.1 is not quite right, the correct code is usually one of these.

Questions about E85.1

Is E85.1 a billable ICD-10-CM code?
Yes. E85.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does E85.1 sit in the tabular list?
Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.