E78.2 — Mixed hyperlipidemia
E78.2 is a billable, specific ICD-10-CM code for mixed hyperlipidemia. It is valid for submission on a claim.
Excludes1 — never code together
These conditions cannot occur together. Billing both on the same encounter is a denial.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Broad- or floating-betalipoproteinemia
- Combined hyperlipidemia NOS
- Elevated cholesterol with elevated triglycerides NEC
- Fredrickson's hyperlipoproteinemia, type IIb or III
- Hyperbetalipoproteinemia with prebetalipoproteinemia
- Hypercholesteremia with endogenous hyperglyceridemia
- Hyperlipidemia, group C
- Tubo-eruptive xanthoma
- Xanthoma tuberosum
Other codes that can never be billed with E78.2
These codes carry an Excludes1 note pointing at E78.2. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading E78.2 alone.
- M67Other disorders of synovium and tendon
Risk adjustment
E78.2 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Medicare coverage
E78.2 is named in 23 Medicare coverage policies — 23 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
- A56416Billing and Coding: Assays for Vitamins and Metabolic Function
- A56422Billing and Coding: Bariatric Surgical Management of Morbid Obesity
- A56675Billing and Coding: Homocysteine Level, Serum
- A56943Billing and Coding: MolDX: Biomarkers in Cardiovascular Risk Assessment
How E78.2 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E78.2.
- Betalipoproteinemia, broad or floating
- Broad- or floating-betalipoproteinemia
- Dysbetalipoproteinemia(familial)
- Xanthelasmatosis(essential)
- Xanthoma(s), xanthomatosis (primary) (familial) (hereditary)
- Broad›beta disease
- Frederickson's hyperlipoproteinemia, type›IIB and III
- Hyperbetalipoproteinemia›with prebetalipoproteinemia
- Hypercholesterolemia›with hyperglyceridemia, endogenous
- Hyperlipemia, hyperlipidemia›combined
- Hyperlipemia, hyperlipidemia›mixed
- Lipoproteinemia›broad-beta
Related codes at this level
Codes that share E78. If E78.2 is not quite right, the correct code is usually one of these.
- E78.0Pure hypercholesterolemia
- E78.1Pure hyperglyceridemia
- E78.3Hyperchylomicronemia
- E78.4Other hyperlipidemia
- E78.5Hyperlipidemia, unspecified
- E78.6Lipoprotein deficiency
- E78.7Disorders of bile acid and cholesterol metabolism
- E78.8Other disorders of lipoprotein metabolism
- E78.9Disorder of lipoprotein metabolism, unspecified
Questions about E78.2
- Is E78.2 a billable ICD-10-CM code?
- Yes. E78.2 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E78.2 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Metabolic disorders (E70-E88).
- What cannot be coded together with E78.2?
- E78.2 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.